Coffee disrupts brain development
نویسندگان
چکیده
منابع مشابه
SMN deficiency disrupts brain development in a mouse model of severe spinal muscular atrophy.
Reduced expression of the survival motor neuron (SMN) gene causes the childhood motor neuron disease spinal muscular atrophy (SMA). Low levels of ubiquitously expressed SMN protein result in the degeneration of lower motor neurons, but it remains unclear whether other regions of the nervous system are also affected. Here we show that reduced levels of SMN lead to impaired perinatal brain develo...
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As you can see the referees find the analysis interesting and important. However, they also raise a number of significant concerns that would have to be resolved in order to consider publication here. Both referees 2 and 3 find that the data at present is not strong enough to support that the effects of cannabis treatment on synaptic plasticity and wiring are mediated via altered JNK/ERK activa...
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Children exposed in utero to cannabis present permanent neurobehavioral and cognitive impairments. Psychoactive constituents from Cannabis spp., particularly Δ(9)-tetrahydrocannabinol (THC), bind to cannabinoid receptors in the fetal brain. However, it is unknown whether THC can trigger a cannabinoid receptor-driven molecular cascade to disrupt neuronal specification. Here, we show that repeate...
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ژورنال
عنوان ژورنال: Nature Reviews Neuroscience
سال: 2013
ISSN: 1471-003X,1471-0048
DOI: 10.1038/nrn3594